Milk Thistle is a herbaceous annual or biennial plant with a dense-prickly flower head and reddish-purple tubular flowers. It is native to the Mediterranean region and has been naturalized in Central Europe, North and South America, and Southern Australia. Milk Thistle has an extensive history of use as an edible plant. In the 1st century AD, Pliny the Elder reported its use for supporting liver health. Theosophists (IV century BC) and Dioscorides (1st century AD) also wrote of its value. The English herbalist, Nicholas Culpeper (1650) claimed it was effective for supporting the normal functioning of the liver. At the turn of the 20th century, Eclectic physicians also used Milk Thistle to support healthy liver function. Much of the modern day research has been conducted in Germany where it is an approved herb in The German Commission E Monographs.
What is Blessed Thistle Used for?
The use of bitter plants to tonify digestion is one of the primary tools in the herbalist’s repertoire. Proper digestion is the foundation of health. Blessed Thistle does contain bitter principles called perquisites which also impart the bitter taste to the wormwood’s (Artemisia) and to (Ginkgo biloba). Bitters stimulate the secretion of digestive juices in the stomach and support the breakdown of fats, supporting a healthy appetite and assisting in the assimilation of nutrients. The tea has been used historically by midwives and nephropathy to support healthy breast milk production.
7 Science-Based Benefits of Milk Thistle
Milk thistle is an herbal remedy derived from the milk thistle plant, also known as Silybum marianum.
This prickly plant has distinctive purple flowers and white veins, which traditional stories say were caused by a drop of the Virgin Mary’s milk falling onto its leaves.
The active ingredients in milk thistle are a group of plant compounds collectively known as silymarin (1Trusted Source).
Its herbal remedy is known as milk thistle extract. Milk thistle extract has a high amount of silymarin (between 65–80%) that has been concentrated from the milk thistle plant.
The silymarin extracted from milk thistle is known to have antioxidant, antiviral and anti-inflammatory properties
In fact, it has traditionally been used to treat liver and gallbladder disorders, promote breast milk production, prevent and treat cancer and even protect the liver from snake bites, alcohol and other environmental poisons.
1. Milk Thistle Protects Your Liver
Milk thistle is often promoted for its liver-protecting effects.
It’s regularly used as a complementary therapy by people who have liver damage due to conditions like alcoholic liver disease, non-alcoholic fatty liver disease, hepatitis and even liver cancer
It’s also used to protect the liver against toxins like antitoxin, which is produced by the death cap mushroom and is deadly if ingested
Studies have shown improvements in liver function in people with liver diseases who have taken a milk thistle supplement, suggesting it could help reduce liver inflammation and liver damage (9Trusted Source).
Although more research is needed on how it works, milk thistle is thought to reduce damage to the liver caused by free radicals, which are produced when your liver metabolizes toxic substances.
One study also found that it may slightly extend the life expectancy of people with cirrhosis of the liver due to alcoholic liver disease (10Trusted Source).
However, the results from studies have been mixed, and not all have found milk thistle extract to have a beneficial effect on liver disease.
Thus, more studies are needed to determine what dose and length of treatment are needed for specific liver conditions
And although milk thistle extract is commonly used as a complementary therapy for people with liver diseases, there’s currently no evidence that it can prevent you from getting these conditions, especially if you have an unhealthy lifestyle.
2. It May Help Prevent Age-Related Decline in Brain Function
Milk thistle has been used as a traditional remedy for neurological conditions like Alzheimer’s and Parkinson’s disease for over two thousand years (13Trusted Source).
Its anti-inflammatory and antioxidant properties mean that it is possibly neuroprotective and could help prevent the decline in brain function you experience as you age (14Trusted Source, 15Trusted Source).
In test-tube and animal studies, silymarin has been shown to prevent oxidative damage to brain cells, which could help prevent mental decline (16Trusted Source, 17Trusted Source).
These studies have also seen that milk thistle may be able to reduce the number of amyloid plaques in the brains of animals with Alzheimer’s disease (18Trusted Source, 19Trusted Source, 20Trusted Source).
Amyloid plaques are sticky clusters of amyloid proteins that can build up between nerve cells as you age.
They are seen in very high numbers in the brains of people with Alzheimer’s disease, meaning that milk thistle could potentially be used to help treat this difficult condition (21Trusted Source).
However, there are currently no human studies examining the effects of milk thistle in people with Alzheimer’s or other neurological conditions like dementia and Parkinson’s.
Moreover, it’s unclear whether milk thistle is well enough absorbed in people to allow adequate amounts to pass through the blood-brain barrier. It’s also unknown what doses would need to be prescribed for it to have a beneficial effect (18Trusted Source).
3. Milk Thistle Could Protect Your Bones
Osteoporosis is a disease caused by progressive bone loss.
It usually develops slowly over a number of years and causes weak and fragile bones that break easily, even after minor falls.
Milk thistle has been shown in experimental test-tube and animal studies to stimulate bone mineralization and potentially be protective against bone loss (
As a result, researchers suggest that milk thistle may be a useful therapy for preventing or delaying bone loss in postmenopausal women (24Trusted Source, 25Trusted Source).
However, there are currently no human studies, so its effectiveness remains unclear.
4. It May Improve Cancer Treatment
It’s been suggested that the antioxidant effects of silymarin may have some anticancer effects, which could be helpful for people receiving cancer treatment (9Trusted Source).
Some animal studies have shown that milk thistle could be useful for reducing the side effects of cancer treatments
It may also make chemotherapy work more effectively against certain cancers and, in some circumstances, even destroy cancer cells
However, the studies in humans are very limited and have yet to show a meaningful clinical effect in people
This may be because people aren’t able to absorb enough to get a medicinal effect.
More studies are needed before it can be determined how silymarin might be used to support people undergoing cancer treatment.
5. It Can Boost Breast Milk Production
One reported effect of milk thistle is that it can boost breast milk production in lactating mothers. It’s thought to work by making more of the milk-producing hormone protactinium.
The data is very limited, but one randomized controlled study found that mothers taking 420 mg of silymarin for 63 days produced 64% more milk than those taking a placebo (37Trusted Source).
However, this is the only clinical study available. More research is needed to confirm these results and the safety of milk thistle for breastfeeding mothers
6. It Could Help Treat Acne
Acne is a chronic inflammatory skin condition. While not dangerous, it can cause scars. People may also find it painful and worry about its effects on their appearance.
It’s been suggested that oxidative stress in the body may play a role in the development of acne (41Trusted Source).
Due to its antioxidant and anti-inflammatory effects, milk thistle may be a useful supplement for people with acne.
Interestingly, one study found that people with acne who took 210 milligrams of silymarin per day for 8 weeks experienced a 53% decrease in acne lesions (42).
However, as this is the only study, more high-quality research is needed.
Have medical questions? Connect with a board-certified, experienced doctor online or by phone. Pediatricians and other specialists available 24/7.
7. Milk Thistle Can Lower Blood Sugar Levels for People With Diabetes
Milk thistle may be a useful complementary therapy to help manage type 2 diabetes.
It’s been discovered that one of the compounds in milk thistle may work similarly to some diabetic medications by helping improve insulin sensitivity and decrease blood sugar (43Trusted Source).
In fact, a recent review and analysis found that people routinely taking silymarin experienced a significant reduction in their fasting blood sugar levels and HbA1c, a measure of blood sugar control (44Trusted Source).
Additionally, the antioxidant and anti-inflammatory properties of milk thistle may also be useful for reducing the risk of developing diabetic complications like kidney disease (43Trusted Source).
However, this review also noted that the quality of the studies was not very high, so more studies are needed before it’s possible to make any firm recommendations (